Arbetsbeskrivning

We are seeking a motivated, self-driven Research and Production Engineer with a strong initiative, curiosity, and hands-on expertise at the lab bench. This role will work closely with our Research and Process Development teams to co-develop methods for the synthesis, purification, and scale-up of single-stranded DNA (ssDNA) production, purification, and quality control.

Key Responsibilities:

● Manufacture ssDNA for both client-driven projects and internal development.

● Maintain thorough and accurate documentation across systems including electronic lab notebooks (ELNs), manufacturing and lab execution systems (MES/LES), laboratory information systems (LIMS), quality management systems (QMS), and process knowledge databases.

● Contribute to the development and optimization of manufacturing and business processes.

● Plan, execute, and troubleshoot experimental and client-facing scientific projects, including optimization of unit operations.

● Report on project progress and key product quality attributes (CQAs). ● Present findings and innovations to internal teams and stakeholders.

● Develop and maintain workflows, standard operating procedures (SOPs), and associated documentation supporting R&D, tech transfer, and quality assurance.

● Perform additional tasks and responsibilities as assigned.

Preferred Qualifications and Skills:

● Bachelor’s degree with 5+ years, or Master’s degree with 3+ years, in molecular or cell biology, biochemistry, biomedical or chemical engineering, or a related field.

● Solid understanding of nucleic acid synthesis and purification, with working knowledge of nucleic acid structure and function.

● Hands-on experience with: PCR, qPCR, RT-PCR, molecular cloning (e.g., Gibson Assembly, Golden Gate), agarose gel electrophoresis, and Fragment Analyzer.

● Advanced techniques such as PAGE, Western blotting, dot/slot blotting, silver staining, AKTA/FPLC, and Bioanalyzer are strongly preferred.

● Familiarity with design of experiments (DoE) and ICH guidelines for product and process development is a plus.

● Experience with lab automation systems and workflows is a strong advantage.

● Demonstrated ability to design experiments with appropriate controls and apply the scientific method rigorously.