Arbetsbeskrivning

Circio Holding ASA is a biotechnology company developing powerful circular RNA vector expression technology for next generation nucleic acid medicine.

Circio has established a unique circular RNA (circRNA) vector expression technology for next generation RNA, DNA and viral therapeutics. The proprietary circVec platform is based on a modular genetic cassette design for efficient biogenesis of multifunctional circRNA inside cells. The circVec platform has applications in multiple therapeutic settings, including genetic medicine, cell therapy and chronic disease. It has demonstrated 70-fold increased RNA half-life and up to 15-fold enhanced protein expression vs. conventional mRNA vector systems in vivo, and has the potential to become a new gold-standard protein expression technology. The circRNA R&D activities are being conducted by the wholly owned subsidiary Circio AB in Stockholm, Sweden.

Are you passionate about molecular biology or immunology and eager to make a real impact in the development of gene and cell therapy?

Circio is currently seeking a research assistant to join the expanding R&D Department of Circio in Huddinge, Stockholm; to manage, spearhead and conduct experimental work towards the optimization and characterization of Circio’s proprietary gene therapy vector platform. In this position, you will contribute to the development of the company’s research programs as well as conduct an extended array of molecular biology and immunology-based assays. In addition, you will work in a fast-paced, exciting, and inspirational environment in-between academia and industry and participate in many aspects of discovery and pre-clinical staged therapeutic development.

As part of our team, you will:

• Support and contribute to research projects in molecular biology or immunology
• (e.g., analyzing RNA and protein yield after transfection, or exploring immune responses to DNA delivery techniques)
• Help design and run experiments in the lab, analyze results, and present your findings
• Collaborate closely with team members, offering ideas and input on ongoing research and development

We’re looking for someone who:

• Has a background in molecular biology, immunology, biotechnology, or a related field (preferable with a master’s degree, 2+ years industry experience or similar)
• Is enthusiastic about lab work and eager to learn new techniques
• Communicates clearly in English and enjoys working in a diverse, team-based setting
• Is curious, detail-oriented, and ready to take initiative with the support of experienced colleagues

It’s a Plus If You Have Experience With:

• Basic lab techniques like cloning, PCR, Western blotting, RT-qPCR, or flow cytometry
• Cell culture, including immune or tumor cells
• Gene delivery methods (viral or non-viral)
• Data analysis and visualization using Excel, Graphpad, Python, R, or similar tools
• Writing scientific reports and summarizing data in powerpoint presentations

Don’t worry if you don’t check every box—we’re happy to train the right person!

Why Join Us?

• Be part of a passionate, international R&D team working on transformative therapies
• Learn from experienced scientists in a supportive, mentorship-focused environment
• Gain exposure to both academic and industry-style research
• Contribute to exciting projects that can make a real difference

If you're looking for your first step into a scientific career outside of academia—or a chance to grow your experience in a dynamic biotech setting—we’d love to hear from you. We can offer varied and exciting work in an innovative and dynamic biotech company. We promise you will develop professionally with challenging tasks in a growing company, as you participate in the development of novel treatments. If you are not already familiar with the biotech industry, we can guarantee a steep learning curve while you experience an informal and supportive company culture.

Please send your CV and cover letter in English to [email protected] by August 15. For additional information please contact Ola Melin, COO, via e-mail as above. All applications will be treated confidentially.