Arbetsbeskrivning

SmartCella Solutions is seeking a highly motivated Research Scientist to join our R&D team. The Research Scientist provides scientific expertise, oversees the planning and execution of projects related to cell culture and molecular lab work, and is accountable for delivering these in a timely manner. As a part of our dynamic team, this role would collaborate closely with other scientists to develop, optimize, validate and execute biochemical and/or cellular assays to support R&D projects. This position requires some weekend work.

Areas of responsibilities will include:

• Lead the design, development, and execution of immunological assays, including: ELISApot, ELISA, FACs, detection of antigen-specific cells, functional assays, single-cell profiling techniques to characterize immune cell populations, identify exploratory biomarkers, and other relevant techniques.
• Develop, optimize, validate and troubleshoot immunological assays and implement new techniques to assess mechanisms of action in a timely manner.
• Evaluate, analyze, review raw data, and present results to scientific groups (internally & externally)
• Keep abreast of scientific and other relevant literatures.
• Work collaboratively in a team environment and independently to deliver against fast timelines.
• Maintain a high standard of experimentation and documentations.

Qualifications needed for the role:

Required:

• PhD in Molecular Biology, Immunology, Immuno-oncology, or relevant field.
• Proven experience in cell culturing, passaging, freeze/thaw, general maintenance of human ES or IPSC or other stem cells.
• Hand-on experience in development and implementation of immunological assays, such as: ELISpot, ELISA, FACs, detection of antigen specific cells, cytokine assays, B cell and T cell based assays, serological assays.
• Experience in conceptualizing and leading innovative assay development and data analysis.
• Demonstrated ability to effectively troubleshoot and solve complex problems.
• Experience in working within a fast-paced team environment with a high degree of self-motivation, flexibility, collaboration and organization.
• Meticulous laboratory approach, careful adherence to protocols and excellent lab notebook documentation.
• Excellent verbal and writing skills for documentation of data, drafting of reports, and communication of progress within team and to manager.

Desired:

• Prior experience in DNA/RNA biology is highly desirable.
• Experience in cell and gene therapy
• Experience with animal disease modelling
• Experience with immune repertoire analyses.
• Other related skills such as cell transfection/electroporation/nucleofection and basic molecular biology skills would be highly valued.
• Strong publication record in an academic background in immunology, immune-oncology or cancer biology
• Working knowledge in RNA therapeutic field
• Fluent in English (writing and speaking), while fluency in Swedish is appreciated.

Interested? Submit your application today! We will review applications on an ongoing basis.

SmartCella is a world-leading biotech company pioneering the future of targeted therapies by combining first-in-class delivery platforms with cutting-edge cell and gene therapies. The SmartCella group consist of SmartCella Holding AB, ProCella Therapeutics AB, SmartWise AB and SmartCella Solutions AB with a total of 82 employees from more than 20 nationalities.